See the attached quarterly trend report for Novel Psychoactive Substances (NPS), provided by the Center for Forensic Science Research and Education.
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https://www.nflis.deadiversion.usdoj.gov/DesktopModules/ReportDownloads/Reports/NFLISDrugSpecialRelease-Fentanyl-FentanylSubstancesStateMaps-2016-2017.pdf